CONTROLLED DRUG RELEASE FROM ORAL DRUG DELIVERY SYSTEM

Abstract

The controlled release of the drug over a prolonged period of time is one of the fundamentals of controlled drug delivery. These dosage forms are necessary in order to sustain the drug concentration over a prolonged period of time. In the past, treating disease states required administering therapeutic agents in several dosages using a standard dosage form, such as tablets. Pharmaceutical polymers play a part in the development of such systems. This article gives a brief summary of the variety of designs for controlled release drug delivery systems in light of the current and future importance of this category of drug delivery system. The drug must be uniformly spread within a carrier system, either at the molecular level or as solid particles, for controlled or sustained drug delivery systems to work. The most common dosage is oral, such as matrix tablets. As a result, matrix tablets are discussed in this review. The release rate of drugs through oral drug delivery systems is affected by a number of things that can change the way matrix tablets are made. The development of this kind of formulation may benefit greatly from this information.